What do you do when you are so dead tired but you still have a ton of work to complete? Any advise on how to juggle work, deadlines and motherhood?

This is what that is practiced in my department. We have a common understanding within the department that once we have left the office, there will be no mention of ongoing work projects. We also will not contact those on leave unless it is the last and only option (i.e. the person on leave is the ONLY one with the information needed to solve a critical issue). With that, work issues are left at work and all of us can focus on our personal stuff once we leave the workplace. The same applies for when we are at work. We will be all focused and in "work mode" during the time spent in the office. If there is any emergency to attend to, we will take urgent leave and not let our personal issue affect our time at work. This way, we give our best and have a healthy work-life balance. Always remember that there is always work to do and you could continue the next day when you are in office. :) Try speaking to your colleagues to see if something could be worked out. If work is getting too demanding, have a chat with your husband and your boss to see if you could switch to some form of a part-time arrangement (if it is a viable option for you). Take some time to consider this as all are important aspects of your life but you must be wary not to get burnt out.