Pwede naman, mama! A few of us pregnant moms actually prefer taking it in the evening kasi mas consistent kami, pero mas better pa rin if you take it with meals para mas ma-absorb ng katawan mo. Best talaga na tanungin mo ang OB mo kung anong best time for you, especially if may other vitamins ka ring iinumin, baka may conflict or something. Some of my friends take theirs with dinner at tumatagal ang benepisyo throughout the night pa, so it works for them din!