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My friend's baby has serious reflux and PD prescribed the medicine. She seek 2nd opinion from another PD and PD recommended her to feed thicken milk powder, Total Comfort and the condition has improved. I believe all medication has its side effects and thus try to weigh the pros and cons. Here are some tips to handle a reflux baby to improve the condition, especially keep your baby upright after each feed. http://www.parenting.com/article/ask-dr-sears-coping-with-babys-acid-reflux

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thanks