experience sharp pain in the uterus, groin, or either side of the lower abdomen. This may or may not be accompanied by a dull ache in the lower abdomen or sides. As your uterus grows, it can stretch the supporting ligaments, creating what is known as round ligament pain. However, abdominal pain during pregnancy can be a sign of a condition that requires medical attention, like a urinary tract infection, miscarriage, preterm labor or preeclampsia. It's always safest to call your doctor about any symptom that concerns you.