Ah, good question! From what I know, most blood donation centers do screen for hormonal contraceptives like Depo, but it usually doesn't automatically disqualify you, kailangan lang mag-declare sa intake form at let them decide based on their specific requirements, kasi bawat center may sarili nilang guidelines. I'd definitely call ahead sa blood bank where you plan to donate (like Philippine Red Cross or sa nearest hospital) para sure ka na, kasi rules can vary at mas mabilis na makukuha mo ang answer directly from them rather than assuming.