Ai, bisul memang sakit especially kalau tersangkut kat baju atau ketika duduk! My go-to approach is keep it clean and dry, kompres with warm water few times a day to help it come to a head faster, a few of my mum friends swear by this, and then once matured, we boleh let it drain naturally or see a doctor if it's really besar or tak sembuh-sembuh. Jangan tahan-tahan nak squeeze jugak, buat lebih teruk je, kalau ada pus atau bertambah merah/bengkak, better check with a doc just to be safe in case kena infection. Paracetamol boleh minum if the pain is too much, and maybe try loose clothing kat area tu to reduce friction.