Why do some vaccines require boosters?

It’s not completely understood why the length of acquired immunity varies with different vaccines. Some offer lifelong immunity with only one dose, while others require boosters in order to maintain immunity. Recent research has suggested that the persistence of immunity against a particular disease may depend on the speed with which that disease typically progresses through the body. If a disease progresses very rapidly, the immune system’s memory response (that is, the “watchdog antibodies” generated after a previous infection or vaccination) may not be able to respond quickly enough to prevent infection—unless they’ve been “reminded” about the disease fairly recently and are already watching for it. Boosters serve as a “reminder” to your immune system. Research is continuing on the persistence of immunity generated by vaccines. Source: https://www.historyofvaccines.org/content/articles/top-20-questions-about-vaccination

Angeline Lim

My famous line amongst my kids is “NO”

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Ah yes, this is something I've asked our pedia about din kasi my son needed boosters for tetanus at school! Basically, some vaccines give long-lasting protection, like measles, you're mostly good for life, but others like tetanus and pertussis need reminders every few years because those diseases spread so fast na ang immune system needs a "heads up" to catch them in time, otherwise by the time your body remembers what to do, you're already sick. It's like your antibodies are sleeping guards, and boosters wake them up to say "hey, stay alert!"

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